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Genetics Biol-143 of the |
Mead Hall Room 131i (909) 607-2774 Office hours: Tuesday & Thursday 1:30-3:30pm |
Lecture: Tuesday & Thursday 9:35am-10:50am Scripps Humanitites Room 119
Textbook: Genetics: Analysis and Principles, 2nd Edition. Robert J. Brooker. McGraw-Hill: 2005. ISBN: 9780072965971
| Schedule of Lectures and Assignments | |
| Tuesday Lecture | Thursday Lecture |
| 1/22 Course Introduction, Genetics, and the History of Heredity | 1/24 Mendelian Genetics - Assignment Solutions |
1/29 Pedigrees & Probability - Assignment Solutions Link to "Facing Life with a Lethal Gene" |
1/31 Chromosome Theory & Cell Division - Assignment Solutions HW due: Mendelian Genetics
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2/5 Complications with Single Genes - Assignment-Solutions
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2/7 Gene Interactions - Assignment-Solutions In class exercises with solutions HW due: Pedigrees & Probabilities and Chromosome theory & Cell Division |
2/12 Quantitative Genetics Reading assignment: Chapter 24 |
2/14 First Midterm Exam Solutions HW due: Single Gene Dynamics and Gene Interactions |
| 2/19 Mapping genes in diploid organisms Assignment Solution | 2/21 Mapping genes in haploid organisms Assignment Solution |
2/26 Creighton & McClintock paper Assignment Solution Creighton & McClintock Paper (pdf) HW due: Creighton & McClintock Assignment |
2/28 DNA: Structure & Function Assignment Solutions HW due: Diploid Mapping & Happloid Mapping
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3/4 DNA: Replication Assignment Solutions
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3/6 DNA: Expression Assignment Solutions HW due: DNA Structure & Function |
| 3/11 Non-Mendelian Inheritance Assignment Solutions | 3/13 Second Midterm Exam Solutions HW due: DNA Replication & Expression |
| 3/18 Spring Break | 3/20 Spring Break |
3/25 Point Mutations Assignment Solutions
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3/27 DNA Repair & Recombination Assignment Solutions HW due: Non-Mendelian Inheritance |
4/1 Chromosome Mutations Assignment Solutions
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4/3 Genome Mutations Assignment Solutions HW due: Point Mutation & DNA Repair/Recombination |
4/8 Chronic Myelogenous Leukemia Assignment Baikie et al. (1960) “A possible specific chromosome abnormality in human chronic myeloid leukæmia.” Nature 188:1165-6 Rowley (1973) "A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and giemsa staining.” Nature 243: 290-293 HW due: CML Assignment |
4/10 Third Midterm Exam Solutions
HW due: Chromosome & Genome Mutations |
| 4/15 CML discussion | 4/17 Molecular Mapping Assignment |
4/22 Physical Mapping Assignment
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4/24 The Human Genome Project "The Human Genome" Pennisi (2001) Science 291(5507): 1177-1180 HW due: Molecular Mapping |
4/29 Transposons Assignment
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5/1 Reverse Genetics Assignment HW due: Physical Mapping |
5/6 Gene Therapy Paper Assignment "Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system" Yant et al. (2000) Nature Genetics 25: 35-41 HW due: Transposons & Reverse Genetics & Paper Questions |
5/8 Senior Final 9:35am
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| 5/15 Regular Final 9am |