EDUCATION
Ph.D. – Molecular Biology, Cornell University Medical College/Sloan-Kettering Institute. Thesis: The role of processing signals in transcription termination by RNA polymerase II. Dr. Erik Falck-Pedersen, thesis advisor.

B.A. – Biology, Swarthmore College.

TEACHING
Assistant Professor - W. M. Keck Science Center of the Claremont Colleges, 2000.

Assistant Professor – Biology Department, North Central College, Naperville IL. September 1997-June 1998.

RESEARCH EXPERIENCE
Post-doctoral Research Fellow – Beckman Research Institute of the City of Hope, Duarte, CA. November 1998-July 2000. Project involves genetic and biochemical studies of pre-mRNA splicing in the yeast Saccharmoyces cerevisiae. Dr. Ren-Jang Lin, principal investigator.

Post-doctoral Research Scientist – University of Pittsburgh School of Medicine, Pittsburgh, PA. September 1993-August 1997. Project involved identification and characterization of trans factor(s) causing differential poly(A) site use in the mouse immunoglobulin heavy chain locus in myeloma versus lymphoma cells using molecular biological and biochemical approaches.  Dr. Christine Milcarek, principal investigator.

RECENT PUBLICATIONS

Papers

Edwalds-Gilbert, G., D.-H. Kim,  S.-H. Kim, Y.-H. Tseng,Y Yu, and R.-J. Lin. 2000. Dominant negative mutants of the yeast splicing factor Prp2 map to a putative cleft region in the helicase domain of DExD/H-box proteins. RNA 6(8):1106-19

Veraldi, K. L., G. Edwalds-Gilbert, C. C. MacDonald, A. M. Wallace, and C. Milcarek. 2000. Isolation and characterization of polyadenylation complexes assembled in vitro. RNA 6:768-777.

Kim, D.-H., G. Edwalds-Gilbert, C. Ren, and R.-J. Lin. 1999. A mutation in a methionine tRNA gene supresses the prp2-1Ts mutation and causes a pre-mRNA splicing defect in Saccharomyces cerevisiae. Genetics 153: 1105-1115.

Martincic, K., R. Campbell, G. Edwalds-Gilbert, L. Souan, M. T. Lotze, and C. Milcarek. 1998. Increase in the 64-kDa subunit of the polyadenylation/cleavage stimulatory factor during the G0 to S phase transition. Proc Natl Acad Sci U S A 95: 11095-100.

Edwalds-Gilbert, G., K. L. Veraldi, and C. Milcarek. 1997. Alternative poly(A) site selection in complex transcription units: means to an end? Nucleic Acids Res 25: 2547-61.

Edwalds-Gilbert, G., and C. Milcarek. 1995. Regulation of poly(A) site use during mouse B-cell development involves a change in the binding of a general polyadenylation factor in a B-cell stage-specific manner. Mol Cell Biol 15: 6420-9.

Edwalds-Gilbert, G., and C. Milcarek. 1995. The binding of a subunit of the general polyadenylation factor cleavage- polyadenylation specificity factor (CPSF) to polyadenylation sites changes during B cell development. Nucleic Acids Symp Ser 33: 229-33.

Edwalds-Gilbert, G., J. Prescott, and E. Falck-Pedersen. 1993. 3' RNA processing efficiency plays a primary role in generating termination-competent RNA polymerase II elongation complexes. Mol Cell Biol 13: 3472-80.

Abstracts (selected)
Edwalds-Gilbert, G., D.-H. Kim, E. Silverman, V. Yu, and R.-J. Lin. 1999. Mutational analysis of Prp2, an RNA-dependent ATPase in the DExD/H-box family. Abstract presented at RNA ’99: The fourth annual meeting of the RNA Society, Edinburgh, Scotland, June 1999.

Veraldi, K.L., K. Martincic, G. Edwalds-Gilbert, and C. Milcarek. 1998. Qualitative and quantitative changes in CstF-64. Abstract presented at RNA’98: The third annual meeting of the RNA Society, Madison, WI, May 1998.

Edwalds-Gilbert, G. and C. Milcarek. 1996. Trans-factors involved in the regulation of RNA processing in B cell development. Abstract presented at RNA’96: The first annual meeting of the RNA Society, Madison, WI, May 1996.

Edwalds-Gilbert, G. and C. Milcarek. 1996. Characterization of polyadenylation-competent nuclear extracts from mouse B-cell lines. Abstract presented at workshop entitled "From transcript to protein: mRNA processing, transport, and translation." Instituto Juan March, Madrid, Spain, March 1996.

MEMBERSHIPS

American Society for Microbiology, 1998-present
American Association for the Advancement of Science, 1986-present